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Obsessive Thoughts, Repetitive Rituals, and Anxiety That Won’t Quit? It Might Be OCD—Or It Might Be Your Hormones

Obsessive Thoughts, Repetitive Rituals, and Anxiety That Won’t Quit? It Might Be OCD—Or It Might Be Your Hormones

June 27, 20253 min read

Obsessive Thoughts, Repetitive Rituals, and Anxiety That Won’t Quit? It Might Be OCD—Or It Might Be Your Hormones

You’ve always been able to keep it together. But lately, your thoughts feel louder. You’re triple-checking the locks. Washing your hands until they’re raw. Replaying the same fear or “what if” in your head over and over. You’re exhausted, mentally and emotionally. And you’re wondering: Is this anxiety, OCD… or something else entirely?

Here’s the truth that doesn’t get talked about enough: obsessive-compulsive tendencies can flare—or even emerge for the first time—during perimenopause and menopause. Why? Because the brain is wired to respond to hormones, especially estrogen and progesterone. When those hormones drop or fluctuate, the brain’s mood-regulating systems go haywire.

Let’s break it down.


What Is OCD?

Obsessive-Compulsive Disorder (OCD) is an anxiety disorder marked by repetitive, unwanted thoughts (obsessions) and ritualistic behaviors or mental acts (compulsions) done to reduce the anxiety those thoughts create.

Obsessions might include:

  • Fear of germs or contamination

  • Intrusive, often disturbing thoughts about harm or taboo subjects

  • Anxiety about things being “just right” or perfectly symmetrical

  • A need to control or prevent catastrophic outcomes

Compulsions are the actions taken to quiet the obsession:

  • Excessive hand washing or cleaning

  • Checking locks, appliances, or “mistakes” repeatedly

  • Repeating words, phrases, or prayers

  • Arranging, counting, touching things in a particular way

  • Avoiding people, places, or situations that trigger obsessive thoughts

OCD isn’t just a “quirk.” It’s a mental health condition that can take over your time, energy, and peace of mind. And for many women, it intensifies in midlife—right when hormones are in full flux.


Why Hormonal Shifts Can Trigger OCD Symptoms

Here’s what’s happening behind the scenes:

  • Estrogen helps regulate serotonin, dopamine, and glutamate—neurotransmitters involved in mood, impulse control, and decision-making. When estrogen dips (especially in perimenopause), serotonin drops, making the brain more anxious, rigid, and obsessive.

  • Progesterone, often called the brain’s “chill pill,” supports GABA—the calming neurotransmitter. When progesterone crashes (which happens years before menopause), GABA signaling weakens, and anxiety skyrockets.

  • Cortisol, your stress hormone, spikes under pressure and amplifies fear-based thought loops, especially when sleep is poor, blood sugar is unstable, or you’re emotionally maxed out.

In short: the perimenopausal brain is inflamed, undernourished, and overstimulated—and OCD loves that environment.


It’s Not Just OCD—It’s the Brain in Hormonal Transition

Even if you’ve never struggled with OCD before, midlife can bring on new-onset obsessive tendencies. Or, if you’ve always had mild OCD or anxiety, this hormonal season can turn the volume way up.

Many women in their 40s and 50s report:

  • Intrusive or repetitive thoughts they can’t “turn off”

  • Excessive worry or fear of something “bad” happening

  • Compulsive checking, cleaning, or reassurance-seeking

  • Difficulty relaxing or switching off the brain

  • Heightened sensitivity to sounds, smells, or disorder

This is real. And it’s not “you going crazy.” It’s your brain crying out for hormonal support.


What Actually Helps

OCD treatment can be powerful—but incomplete if you ignore the hormonal piece. Here's what a full-spectrum approach looks like:

✅ Cognitive Behavioral Therapy (CBT) with Exposure and Response Prevention (ERP)
✅ Targeted medication (SSRIs, if appropriate)
Bioidentical Hormone Replacement Therapy (BHRT)—especially progesterone for GABA support and estrogen for serotonin balance
✅ Sleep restoration, blood sugar balance, and nervous system regulation
✅ Mindfulness and somatic practices to help calm the limbic system

For many women, BHRT becomes the turning point—restoring the brain's biochemical balance and making therapy and medication more effective.


You’re Not Alone—And You’re Not Broken

Whether you've been diagnosed with OCD or you’re just noticing intense thought spirals that won’t quit, you deserve support that addresses the real root. You’re not just “anxious.” You’re in the middle of a massive neuroendocrine shift—and your brain needs backup.

👉 Book your consult now at getmerva.com
👉 Let’s evaluate your hormones, mental health, and nervous system—and build a plan that puts you back in the driver’s seat of your mind.

Dr. Betty Murray is a PhD researcher, nutritionist and functional medicine practitioner and CEO & founder of The Menrva Project. She has spent the last 20 years, dedicated to women's health and helping women sail through menopause as if it never happened.

Dr. Betty Murray

Dr. Betty Murray is a PhD researcher, nutritionist and functional medicine practitioner and CEO & founder of The Menrva Project. She has spent the last 20 years, dedicated to women's health and helping women sail through menopause as if it never happened.

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