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Why You Keep Getting UTIs (And What Estrogen Has to Do With It)

Why You Keep Getting UTIs (And What Estrogen Has to Do With It)

June 04, 20253 min read

Why You Keep Getting UTIs (And What Estrogen Has to Do With It)

If you're a woman in perimenopause or postmenopause and you're constantly battling urinary tract infections (UTIs), you’re not alone—and you’re not crazy. Recurrent UTIs are not just a hygiene issue or “bad luck.” More often than not, they’re a direct result of one thing: estrogen loss.

Yep. Estrogen doesn’t just manage your cycle or mood—it’s also your bladder and vaginal tissue’s best friend. And when it starts to decline (or disappear altogether), those tissues become thinner, drier, and more prone to inflammation and infection.


What’s Really Causing the Spike in UTIs?

Estrogen helps maintain the strength, flexibility, and acidity of the urogenital tissues. When estrogen drops, here’s what happens:

  • The vaginal pH rises, allowing bad bacteria like E. coli to thrive

  • The urethra and bladder lining thin, losing their protective barrier

  • Lubrication disappears, increasing irritation and micro-tears

  • The microbiome shifts, wiping out good bacteria that once kept you balanced

Add in sex, dehydration, or certain birth control methods—and boom, you’ve got the perfect storm for a UTI.


The Stats You Need to Know

💥 Up to 53% of postmenopausal women not using vaginal estrogen experience recurrent UTIs
💥 Vaginal estrogen can reduce UTI risk by 36%–75%
💥 One study showed a 75% drop in infections with intravaginal estriol
💥 51.9% of women had fewer UTIs within a year of starting vaginal estrogen—and one-third had none at all

This isn’t fluff. It’s evidence-based, targeted, and life-changing for women in midlife and beyond.


Symptoms of a UTI

Some are obvious. Others, especially in older women, are sneaky:

  • Burning or stinging during urination

  • A constant, urgent need to pee

  • Pelvic discomfort or pressure

  • Blood in the urine

  • Fever (especially with back pain = emergency)

  • Confusion or mental decline in older women (yes, this can be a UTI sign)

  • No symptoms at all—and still at risk for sepsis


The Real Danger: Sepsis

UTIs aren’t just uncomfortable. Left untreated, they can become deadly.

📌 Sepsis—a severe, body-wide response to infection—can start with a UTI
📌 Globally: 49 million cases/year, 11 million deaths
📌 In the U.S.: 1.7 million cases/year, ~350,000 deaths
📌 Sepsis causes 1 in 3 hospital deaths

Let that sink in. Recurrent UTIs are not just a nuisance—they’re a real health threat.


What You Can Do Right Now

Sure, antibiotics treat the infection—but they don’t fix the why. That’s where vaginal estrogen therapy comes in.

This isn’t systemic HRT. It’s a tiny localized dose, delivered right to the vaginal and urinary tissues via creams, pessaries, or suppositories. It’s safe, effective, and doesn’t increase breast cancer risk when used appropriately.

Pair it with:

  • Hydration

  • Post-sex urination

  • Avoiding spermicides or diaphragms

  • Wiping front-to-back

  • Stress and cortisol management

  • Functional medicine testing to check your hormones, gut, and immune health


Bottom Line

If you're dealing with frequent UTIs after 40, your declining estrogen may be the real culprit—and vaginal estrogen therapy may be your answer.

It’s not just about comfort. It’s about reclaiming your confidence, your intimacy, and your long-term health.


Your Next Step

Tired of treating infections instead of preventing them? It’s time to stop the cycle. Let’s evaluate your hormone levels and see if vaginal estrogen—or full hormone therapy—is the right move for you.

👉 Book your consult now at getmerva.com

Dr. Betty Murray is a PhD researcher, nutritionist and functional medicine practitioner and CEO & founder of The Menrva Project. She has spent the last 20 years, dedicated to women's health and helping women sail through menopause as if it never happened.

Dr. Betty Murray

Dr. Betty Murray is a PhD researcher, nutritionist and functional medicine practitioner and CEO & founder of The Menrva Project. She has spent the last 20 years, dedicated to women's health and helping women sail through menopause as if it never happened.

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